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Are Psychedelics A Potential Treatment For OCD?

Psychedelics have long been anecdotally known to inspire and support behavioral change especially in response to compulsive and addictive behavior patterns. Many individuals actively utilize psilocybin microdosing to support them in smoking cessation as well as the treatment of drugs and alcohol dependency, but how about other compulsive behaviors linked to obsessive-compulsive disorder?

The New Atlas science journal published a great article highlighting the potential role of dysfunctional default mode networks (DMN) in obsessive-compulsive disorders and the likely role psilocybin can play in "resetting" the healthy functions of these networks. The DMN are a large-scale interconnected collection of brain regions responsible for self-reflection and daydreaming. Imaging studies suggest that psilocybin works to "disintegrate" resting-state networks in the brain such as the DMN. Simply put, psilocybin seems to break existing brain networks and allow for new healthier connections to be formed; this is more commonly known as enhanced neuroplasticity.

"My sense is that, in general, psilocybin therapy is enhanced by placing it within a wider psychotherapeutic program: it's well established now that there is an 'afterglow' period following a psychedelic session, where there is an enhanced level of psychological and neurological flexibility,” Jacobs tells New Atlas. “I suspect that in most conditions, this period of malleability is a powerful opportunity to make positive changes, which therapy can help.”


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The perspectives and recommendations on this website are not made by a medical professional and should not be considered medical advice. Readers are encouraged to consult their physician before taking any supplements or substances. 


While we believe that psychedelic medicines must be decriminalized, psychedelic substances are still considered  "Schedule I" substances in the US and continue to be subject to strong enforcement across nearly all states. The reader is responsible for checking their local rules and regulations and making informed decisions with all risk considerations. Microdose Guru does accept liability for its readers' personal choices. We are a strictly educational platform. 

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