Psilocybin and Treatment-Resistant Depression

Treatment-Resistant Depression (TRD) is one of the most debilitating chronic mental health conditions characterized as a depression that lasts for many years and does not respond to a variety of conventional treatments and is accompanied by suicidal ideation. Some estimates suggest that as many as 60% of individuals with depression qualify as TRD patients.

While there are currently no definitively effective TRD treatments available, psilocybin therapy seems to offer a glimmer of hope for the patients. The Green Prophet publication recently published an article outlining the promising effects of psilocybin-therapy in the early studies associated with TRD.

"The use of psychedelics in healthcare is not new—historical evidence of many cultures used ‘magic mushrooms’ to achieve a state of enlightenment. To unlock the brain, creativity, and existential thoughts is part of the psychedelic ‘trip.’ And now, western medicine is taking a look at the potential to use it to penetrate treatment-resistant depression and provide relief."

"... Johns Hopkins University released an exciting study. Published in JAMA Psychiatry, the clinical trial revealed that 71% of patients experienced a clinically significant response to psilocybin therapies. And 54% of participants met the clinical criteria for “remission of depression.”"

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