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3 Functional Mushrooms That Support Microdosing

Updated: May 28, 2022

Functional mushrooms have long been revered in ancient Chinese and Ayurvedic medicine for their potent health benefits including nervous system health, immune-boosting, digestive support, cognitive support, and even as an effective treatment for some types of cancer to name a few.

I utilize a variety of functional mushrooms for my personal health, as well as supportive and balancing supplements for the Personalized Microdosing Protocols and Integrative Mental Health Protocols I design for clients in my practice. Last year, I conducted an experiment with a hand full of microdosing clients; some microdosing with only psilocybin and others supplementing functional mushrooms in addition, at the end of the 4-month long protocol, those who were supplementing functional mushrooms reported more profound and lasting changes ranging from moderate reduction to complete elimination of fatigue, anxiety, OCD, substance use, and depression. Although this is far from a credible scientific study, the anecdotal evidence has been consistent. I now recommend functional mushrooms supplementation to all my clients as a foundation for their physical and mental health.

Here are my top 3 recommendations:

Lion's Mane Mushrooms

Lion's Mane is an ancient healing mushroom from Asia with reported medicinal uses dating thousands of years back. Lion's Mane has a distinct white "pom-pom" look that resembles a lion's mane!

Lion's Mane is known as a "brain boosting" supplement. Chinese Buddhist monks used Lion’s Mane powder in their tea, claiming it helped them focus on their meditation and increase overall brain power. Contemporary scientific studies are beginning to validate these claims.

Some of the reported benefits of LLion's Mane include:

  • Neurological Health

  • Mood & Mental Health

  • Focus, Memory, Cognition, and Sleep

  • Additional Lion’s Mane Mushroom Health Benefits

Lion's Mane mushrooms are my #1 choice for supplementation while microdosing. Their healing effect on the nervous system and brain functions makes them an ideal candidate for enhancing and supporting your microdose practice. In fact, the proprietary blend that I personally utilize in microdosing contains the maximum daily dose of Lion's Mane!

Reishi Mushrooms

Reishi mushrooms are known as "The King Of Mushrooms" and for good cause. Evidence of the medicinal use of Reishi dates back to 4000 years ago. Reishi is also known as the "Immortality Mushroom" for its superb antioxidant qualities. This fungus contains over 400 different bioactive compounds helping the bodily systems function best on a cellular level. It is one of the world’s most effective adaptogens because it helps the body and mind adapt fluidly to health stressors and maintain allostasis.

Some of the reported benefits of reishi include:

  • Alleviating occasional stress and restlessness

  • Supporting restful sleep and a calm mind

  • Supporting lung and respiratory health

  • Supporting balanced blood sugar levels

  • Supporting the immune system

  • Supporting lower urinary tract

Reishi mushrooms are a great addition to your microdosing practice because of their soothing, balancing, and calming qualities on the nervous system.

Cordyceps Mushrooms

Cordyceps mushrooms are in fact parasitic fungi! They are formed when spores land on an insect and begin to germinate eventually devouring the insect and turning it into a mushroom! I am forever fascinated by this incredible transformation although it sure is creepy!

Cordyceps are used in many traditional medicines since AD 620; they are especially celebrated in Chinese medicine as "nerve tonic", and "peak performance" mushrooms in the west. They are predominantly known for boosting vigor and vitality.

Some of the reporter benefits of cordyceps include:

  • Traditional Chinese Medicinal Uses (nourishing yin, boosting yang, and supporting kidneys)

  • Increase Exercise & Cognitive Performance

  • Support Healthy Inflammation Response

  • Support Healthy Testosterone Levels

  • Enhance Libido

  • Maintain Blood Sugar Balance

  • Maintain Heart Health

  • Soothe Everyday Worry

Cordyceps supports your microdosing practice by boosting vitality, cognitive functions, and their superb stress-mitigating qualities.

A Word On Sourcing

With the rise in popularity of functional mushrooms, unfortunately, there are many questionable and even dangerous products on the market. Aside from inaccurate dosage, heavy fillers, and inaccurate ingredients, cheap functional mushrooms often also mean lax production standards with the potential for toxic mold in your product.

Another common challenge in sourcing is that many companies market "mushroom blends" with little to no transparency about the actual quantities of each type in the blend making effective dosage control practically impossible.

When choosing a functional mushroom brand, the following simple precautions are recommended:

  • Purchase from reputable suppliers only

  • Ethical producers provide easy access to 3-rd party lab testing results

  • Avoid "blends" that do not specifically outline every ingredient and its quantity

Follow the link above to thoroughly vetted and trusted sources.


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The perspectives and recommendations on this website are not made by a medical professional and should not be considered medical advice. Readers are encouraged to consult their physician before taking any supplements or substances. 


While we believe that psychedelic medicines must be decriminalized, psychedelic substances are still considered  "Schedule I" substances in the US and continue to be subject to strong enforcement across nearly all states. The reader is responsible for checking their local rules and regulations and making informed decisions with all risk considerations. Microdose Guru does not endorse or accept liability for its readers' personal choices.  

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